Buffer Z®

BUFFER Z®

Buffer Z by Brexham is a medical-grade anesthetic buffering powder designed to transform the patient experience. By rapidly neutralizing the natural acidity of local anesthetics (like Lidocaine), Buffer Z brings the solution to a physiologic pH (7.4) before injection.

Key Benefits

  • Immediate Onset: Significantly reduces the “waiting time” for anesthesia to take effect, allowing for faster procedure starts.

  • Enhanced Comfort: Eliminates the sharp “sting” of acidic injections, providing a more comfortable experience for anxious patients.

  • Reliable Efficacy: Improves the predictability of nerve blocks, even in infected or inflamed tissue where standard anesthetics often struggle.

  • Sterile Dosing: Available in 50 single-use sachets to ensure maximum clinical purity and easy integration into your workflow.

Reliable

Onset

Comfortable

Buffer Z is formulated as a high-purity, medical-grade alkalizing agent. Its composition is engineered for rapid solubility and chemical stability when mixed with local anesthetics.

  • Active Ingredient: Sodium Bicarbonate

    • A refined, pharmaceutical-grade powder that acts as the primary buffering agent to elevate the anesthetic’s pH from acidic levels (approx. 3.5–5.0) to a physiologic level (approx. 7.4).

 

  • Excipients & Stabilizers: Micro-Crystalline Stabilizers: Ensures the powder remains free-flowing and prevents clumping in high-humidity dental environments.

 

  • Rapid-Dissolve Catalyst: A proprietary inert compound that ensures the powder dissolves clear in seconds without leaving residue or particulates.

     

Properties of Buffer Z

  • pH Neutralization: Elevates the pH of local anesthetics from highly acidic levels (approx. 3.5–5.0) to a physiologic range (approx. 7.35–7.45) instantly.

  • Chemical Synergy: The reaction between Buffer Z and the anesthetic’s hydrochloric acid releases small amounts of Bicarbonate sodium, which acts as a local potentiator, further numbing the nerve trunk.

  • Ionization Balance: Increases the concentration of un-ionized (lipid-soluble) anesthetic molecules. Since only un-ionized molecules can cross the nerve membrane, Buffer Z ensures more active drug reaches the target nerve immediately.

Documentation